Dr. Ravindra Kumar M. Sc., Ph.D.
Scientist D
ICMR-National Institute of Research in Tribal Health
Profile
Dr Ravindra Kumar has expertise in human genetic disorders especially hemoglobinopathies. He is currently contributing to the National Sickle Cell Anemia Elimination Mission.
Research Interests
- Genetics
- Molecular Hematology
- Hemoglobinopathies
Scientific Staff
- Sh. ANUP KUMAR VISHWAKARMA - TECHNICIAN (1)
- MS. MALA PRAJAPATI - TECHNICIAN-A
- Sh.PANKAJ DHEER -TECHNICAL ASSISTANT
- Ms PALAK JAIN -TECHNICIAN (1)
Past Research students
- Co Supervised 8 MD Students and 6 DM Students.
Ongoing research projects
- Establishment of Center of Excellence in SCD
- Mission Program on Pediatric Rare Genetic Disorders
Current research collaborators
N/A
Past research collaborators
N/A
Research in news
N/A
Award/Recognition/Honours
- Dhirendra Nath Das Best paper published award by Indian Society of hematology and blood transfusion presented at Hematocon 2015 conference at Bangalore 5th to 8th Nov 2015.
- Young Scientist Award under DST-Fast Track Scheme Aug 2012.
- Research Associate Award by Council of Scientific and Industrial Research (CSIR) March 2012.
- Best oral presentation award in International Conference of Genomic and Biomedical Research organized by Human Genetic Center, Department of Zoology, Gujarat University in Jan 2009.
- Lectureship Exam (LS-NET), conducted by Council of Scientific and Industrial Research (CSIR) and University Grant commission (UGC) in Dec 2007.
- Graduate Aptitude Test in Engineering (GATE) in Jan 2007 conducted by Indian Institute of Technology.
- Junior Research Fellowship Exam (JRF-NET), conducted by Council of Scientific and Industrial Research(CSIR) and University Grant commission (UGC) in June 2007 under UGC Scheme.
- Junior Research Fellowship Exam (JRF-NET), conducted by Council of Scientific and Industrial Research(CSIR) and University Grant commission (UGC) in Dec 2006 under CSIR Scheme.
Workshop/Conference Organized
- State Level SCD Conference Madhya Pradesh on 3 Jan 2024 jointly organized by NASCO and NHM Bhopal.
- Symposium on Sickle Cell Disease in India on 22 and 23 Feb 2023
- Conference on Holistic Management of Sickle Cell Disease on World Sickle Cell Day, 19 Jun 2022
- Webinar on “Sickle Cell Disease: Global Perspective and Indian Scenario” on World Sickle Cell Day, 19 June 2021
- Hands on Training program for pathologists and technician on “Screening and diagnosis of hemoglobinopathies”. March 2020 at ICMR-NIRTH, Jabalpur
- Hands on Training program for pathologists and technician on “Screening and diagnosis of hemoglobinopathies”. August and September 2019 at ICMR-NIRTH, Jabalpur
- Orientation Program for CMO/CMHO/BMO on Hemoglobinopathies, Diagnosis, Prevention and management. September 2018 at ICMR-NIRTH, Jabalpur
- One Day Seminar on Organization and Ethics of Biomedical Research Publications on 1st Jun 2018 at ICMR-NIRTH, Jabalpur
- One Day CME on Thalassemia on 8th May 2016 at Sri Aurobindo Medical College and Post Graduate Institute, Indore
- One Day CME on Frontiers in Management of Thalassemia at Sri Aurobindo Medical College and Post Graduate Institute, Indore on 31st August 2014 with 2 CME credits by Madhya Pradesh Medical Council
- Five-day hands-on workshop and symposium on advanced laboratory practice in Molecular and Forensic Medicine from 16th -20th 2013 at Sri Aurobindo Medical College and Post Graduate Institute, Indore
Academic contributions
Ph. D.: Nil
Masters dissertation: 6
Papers published: 111
Research Grants
S no. | Title of Project | Funding Agency | Duration |
---|---|---|---|
1 | Genetic Predisposition of Premature Ovarian failure | SERB-DST | Jul 2012 to July 2016 |
2 | Evaluation of paper-based screening test for Sickle cell anemia. | ICMR (Intramural) | April 2018 to March 2019 |
3 | Community-wide screening for Mtb DNA in sputum samples | ICMR (Intramural) | Jan 2020 to Dec 2020 |
4 | Establishment of Center of Excellence in SCD | NHM, Bhopal | June 2022 to Dec 2023 |
5 | To study the dynamics of sickling inside blood capillary mimicking microfluidics system to fabricate a portable point-of-care electronic device for the detection of sickle cell disease | ICMR, New Delhi | Jan 2022 to Dec 2025 |
6 | Mission Program on Pediatric Rare Genetic Disorders | DBT, New Delhi | March 2022 to March 2027 |
Publications
Research Publications (Last 7 Years)
- Gupta P, Shrivastava S, Kumar R. Musculoskeletal complications in sickle cell disease: Pathophysiology, diagnosis and management. Best Pract Res Clin Rheumatol. 2025 Jan 16:102033. doi: 10.1016/j.berh.2025.102033. IF: 4.5
- Nambison NKM, Dwivedi AD, Kumar S, Goel G, Prasad P, Singh G, Rajasubramaniam S, Kumar R. Population-based Research in AYUSH: Lessons from Study among Particularly Vulnerable Tribal Groups to Determine Burden of Sickle Cell Disorders. Journal of Applied Sciences and Clinical Practice. 2024;5(3):138-144.
- Seth T, Udupi S, Jain S, Bhatwadekar S, Menon N, Jena RK, Kumar R, Ray S, Parmar B, Goel AK, Vasava A, Dutta A, Samal P, Ballikar R, Bhat D, Dolai TK, Bhattacharyya J, Shetty D, Mistry M, Jain D. Burden of vaso-occlusive crisis, its management and impact on quality of life of Indian sickle cell disease patients. Br J Haematol. 2025 Jan;206(1):296-309. doi: 10.1111/bjh.19829. IF: 5.2
- Gupta P, Kumar R. Targeting ICAM1 to Ameliorate Vaso-Occlusion and Inflammation in Sickle Cell Disease. Eur J Haematol. 2024 Dec;113(6):730-737. doi: 10.1111/ejh.14313. IF: 2.3
- Rao E, Patel D, Saxena N, Saha KB, Kumar R. Ameliorating Mental Health Issues in Sickle Cell Disease Patients: A Viewpoint. Hemoglobin. 2024;48(3):212-213. doi: 10.1080/03630269.2024.2356607. IF: 1.2
- Sondhiya G, Manjunathachar HV, Singh P, Kumar R. Unveiling the Burden of Scrub Typhus in Acute Febrile Illness Cases across India: A Systematic Review and Meta-analysis. Indian J Med Res. 2024;159(6):601-618. doi: 10.25259/ijmr_1442_23. IF: 2.7
- Gupta P, Choudhari V, Kumar R. Exploring the genetic mechanisms: SELP gene's contribution to alleviating vaso-occlusive crisis in sickle cell disease. Gene. 2024;928:148805. doi: 10.1016/j.gene.2024.148805. IF: 3.1
- Gupta P, Kumar R. Nitric oxide: A potential etiological agent for vaso-occlusive crises in sickle cell disease. Nitric Oxide. 2024. S1089-8603(24)00017-X. doi: 10.1016/j.niox.2024.01.008. Epub ahead of print. PMID: 38316197. IF: 3.9
- Patel D, Kumar R. Community health workers in India should be trained to offer genetic counselling for rare diseases. Nat Med. 2024 Feb;30(2):319. doi: 10.1038/s41591-023-02748-z. PMID: 38200260. IF: 82.9
- Rao E, Chandraker SK, Singh MM, Kumar R. Global distribution of β-thalassemia mutations: An Update. Gene. 2023 Nov 23:148022. doi: 10.1016/j.gene.2023.148022. Epub ahead of print. PMID: 38007159. IF: 3.5
- Gupta P, Singh P, Das A, Kumar R. Determinants of tuberculosis: an example of high tuberculosis burden in the Saharia tribe. Front Public Health. 2023 Oct 18;11:1226980. doi: 10.3389/fpubh.2023.1226980. PMID: 37920577; PMCID: PMC10619692. IF: 5.2
- Singh MPSS, Kumar R, Patel P, Uikey R, Mun A, Shanmugam R. Hemoglobinopathies Among Patients Referred to Single Centre in Central India: An Observational Study. Indian J Clin Biochem. 2025 Jan;40(1):121-126. doi: 10.1007/s12291-023-01151-2. Epub 2023 Sep 21. PMID: 39835230; PMCID: PMC11741957. IF: 2.1
- Narayan A, Shrivastava V, Kumar R. Excerpt of Symposium on Sickle Cell Disease in India. Current Science. 2023;125(7):715-7. IF: 1.169
- Gupta P, Kumar R. GTP cyclohydroxylase1 (GCH1): Role in neurodegenerative diseases. Gene. 2023;888:147749. doi: 10.1016/j.gene.2023.147749. PMID: 37652170. IF: 3.5
- Kumar R, Chandraker SK, Das A. Controlling Sickle Cell Disease: The need of the hour. Clinical Epidemiology and Global Health. 2023;21:101302. doi: 10.1016/j.cegh.2023.101302. IF: 2.6
- Srivastava SKumar R. Is hyperleptinemia associated with gallstone disease? A systematic review and meta-analysis. Indian J Gastroenterol. 2023;42(3):324-331. doi: 10.1007/s12664-022-01332-6. IF: 2.00
- Shrivastava S, Kumar R, Khan S, Kavishwar A, Gupta A, Kaur H, Das M, Sharma R, Chakma T . Health profile of people living in the Gare Palma mining area of Tamnar block, Raigarh, Chhattisgarh, India. Front. Public Health. 2023;11:1010025. doi: 10.3389/fpubh.2023.1010025. IF: 6.461
- Shrivastava S, Kumar R, Shandil N, Saha KB, Das A. Letter: A Pilot Health and Nutritional Assessment of Tribes Living in a High Altitude District of Himachal Pradesh, India. High Alt Med Biol. 2023 Mar;24(1):79-80. doi: 10.1089/ham.2022.0110. PMID: 36516111. IF: 2.183
- Chandraker SK, Kumar R. Biogenic biocompatible silver nanoparticles: a promising antibacterial agent. Biotechnol Genet Eng Rev. 2024 Dec;40(4):3113-3147. doi: 10.1080/02648725.2022.2106084. PMID: 35915981. IF: 4.20
- Kumar R, Rajasubramaniam S, Das A. Sickle cell disease in India: Prevention-driven social and public health implications. Clinical Epidemiology and Global Health. 2022;15:101047. doi: 10.1016/j.cegh.2022.101047. IF: 2.6
- Kumar R. Neglecting borderline HbA2 (3.2–3.9%) may impede prevention programs for thalassemia. Clinical Epidemiology and Global Health. 2022;13:100964. doi: 10.1016/j.cegh.2022.100964. IF: 2.6
- Dixit N, Shaw CK, Varshney GA, Kumar R, Saini PA, Verma P. Endocrinal Complications in Children and Adolescents with Thalassemia Major in Central India: An Observational Study. Indian J Pediatr. 2022;89(10):983-988. doi: 10.1007/s12098-021-03883-6. PMID: 34480715. IF: 5.319
- Mun A, Kumar R, Tiwari S, Uikey R, Thakur P, Mishra S, Chakma T, Shanmugam R. First Observation of Compound Heterozygosity for Hb S/Hb Lepore-Hollandia in India. Indian J Hematol Blood Transfus. 2022;38(1):187-190. doi: 10.1007/s12288-021-01475-0. PMID: 34334973. IF: 0.900
- Kumar R, Das A. The Potential of mHealth as a Game Changer for the Management of Sickle Cell Disease in India. JMIR Mhealth Uhealth. 2021 Apr 13;9(4):e25496. doi: 10.2196/25496. PMID: 33847598. IF: 4.31
- Kumar R, Mishra S, Gwal A, Shanmugam REvaluation of Paper-Based Point of Care Screening Test for Sickle Cell Disease. Indian J Clin Biochem. 2022 Apr;37(2):185-191. doi: 10.1007/s12291-021-00962-5. PMID: 35463103.
- Kumar R R, Yadav R, Mishra S, Singh MPSS, Gwal A, Bharti PK, Rajasubramaniam S. Krüppel-like factor 1 (KLF1) gene single nucleotide polymorphisms in sickle cell disease and its association with disease-related morbidities. Ann Hematol. 2021 Feb;100(2):365-373. doi: 10.1007/s00277-020-04381-z. PMID: 33388857. IF: 3.673
- Kumar R, Mishra S, Shrivastava S. A meta-analysis of endothelial nitric oxide synthase gene T786C polymorphism as a risk factor for acute chest syndrome in sickle cell disease. Meta Gene. 2021;27:100827. doi: 10.1016/j.mgene.2020.100827.
- Kumar R, Mishra S, Uikey RS, Gwal A, Mun A, Bharti PK, Shanmugam R.De Novo Heterozygous Hb G - Waimanalo Variant in a sickle cell disease patient of Indian tribe. J Clin Pathol. 2021;74:336–338. doi: 10.1136/jclinpath-2020-206589. IF: 3.411
- Manjunathachar HV, Barde PV, Raut CG, Tiwari P, Chouksey V, Gowda K, Kumar R, Das A Determination of cut-off of diagnostic ELISA for Scrub typhus in endemic setup: Central India. J Vector Borne Dis. 2021 Jan-Mar;58(1):90-93. doi: 10.4103/0972-9062.316272. IF: 1.688
- Chourasia S, Kumar R, Singh MPSS, Vishwakarma C, Gupta AK, Shanmugam R. High Prevalence of Anemia and Inherited Hemoglobin Disorders in Tribal Populations of Madhya Pradesh State, India. Hemoglobin. 2020 Nov;44(6):391-396. doi: 10.1080/03630269.2020.1848859. PMID: 33222570. IF: 0.526
- Manjunathachar HV, Singh KN, Chouksey V, Kumar R, Sharma RK, Barde PV. Prevalence of Torch infections and its associated poor outcome in high-risk pregnant women of central India: Time to think for prevention strategies. Indian J Med Microbiol. 2020;38:379-84. IF: 0.900
- Kumar R, Singh MPSS, Mahapatra S, Chaurasia S, Tripathi MK, Oommen J, Bharti PK, Shanmugam R. Fine Mapping of Glucose 6 Phosphate Dehydrogenase (G6PD) Deficiency in a Rural Malaria Area of South West Odisha Using the Clinical, Hematological and Molecular Approach. Mediterr J Hematol Infect Dis. 2020 Mar 1;12(1):e2020015. doi: 10.4084/MJHID.2020.015. PMID: 32180910; PMCID: PMC7059741. IF: 1.586
- Kumar R, Shanmugam R Red Cell Indices in Screening of Thalassemia Trait During Antenatal Period. J Obstet Gynaecol India. 2020 Apr;70(2):179-180. doi: 10.1007/s13224-019-01262-y. Epub 2019 Aug 22. PMID: 32255960; PMCID: PMC7109241.
- Kumar R, Patel P, Gwal A, Bharti PK, Colah R, Rajasubramaniam S. Clinico-Hematological Presentation of Rare Hemoglobin Variant (HB-O Indonesia) in 3 Families. Indian J Hematol Blood Transfus. 2019 Jul;35(3):596-598. doi: 10.1007/s12288-019-01125-6. Epub 2019 Apr 17. PMID: 31388286; PMCID: PMC6646446. IF: 1.615
- Singh MM, Kumar R, Tewari S, Agarwal S. Association of GSTT1/GSTM1 and ApoE variants with left ventricular diastolic dysfunction in thalassemia major patients. Hematology. 2019;24(1):20-25. doi: 10.1080/10245332.2018.1502397. IF: 1.315
- Kumar R, Rajasubramaniam S. Hurdles in Thalassemia Management. NIRTH Update. 2018; 3(1):2-3.
- Tripathi P, Kumar R, Agarwal S. Spectrum and hematological profile of hereditary anemia in North Indians: SGPGI experience. Intractable Rare Dis Res. 2018 Nov;7(4):258-263. doi: 10.5582/irdr.2018.01093. PMID: 30560018; PMCID: PMC6290850.
- Nema N, Verma S, Kumar R Investigation of methylenetetrahydrofolate reductase C677T and factor V Leiden mutation as a genetic marker for retinal vein occlusion. Taiwan J Ophthalmol. 2018 Apr-Jun;8(2):99-103. doi: 10.4103/tjo.tjo_43_17. PMID: 30038889; PMCID: PMC6055313.
- Singh MM, Kumar R, Tewari S, Agarwal S. No Association of Genetic Markers with Carotid Intimal Medial Thickness in β-Thalassemia Major Patients. J Pediatr Genet. 2018 Mar;7(1):19-22. doi: 10.1055/s-0037-1608796. Epub 2017 Dec 6. PMID: 29441217; PMCID: PMC5809161.
- Rishi L, Bhandari M, Kumar R. Can bariatric surgery delay the need for knee replacement in morbidly obese osteoarthritis patients? J Minim Access Surg. 2018 Jan-Mar;14(1):13-17. doi: 10.4103/jmas.JMAS_129_16. PMID: 28695875; PMCID: PMC5749191. IF: 1.282