Dr. Vijay Nema M. Sc., Ph.D.
Scientist F
ICMR-National Institute of Research in Tribal Health
Profile
Dr. Vijay Nema has recently joined NIRTH after his transfer from NITVAR. His area of work involves M. tuberculosis drug discovery, alternative medicine and microbiome research
Research Interests
- Target conservation and inhibitor search for essential genes of M. tuberculosis.
- Metagenomic analysis of different microbiomes relevant to human health.
- Viromics.
Scientific Staff
N/A
Past Research students
- Postdoctoral work: 'Characterization of Novel antagonizers for chemokine G-protein coupled receptor' under ICMR Postdoctoral Fellowship. Dr. Amit Dubey (Dec 2017-May 2020).
- PhD awarded: Dr. Sushama Jadhav - "Study on Intracellular Expression of HIV-1 nef Virotoxin and its Role in Neuro-Inflammation" (Symbiosis International University- April 2022).
- PhD ongoing: "Exploration and validation of new drug targets for tackling antimicrobial resistance in Mycobacterium tuberculosis."
- PhD ongoing: "An exploratory study on modulation in human gut microbiota post Naturopathy regimen: A single arm open labeled exploratory study."
- PhD ongoing: "Establishment and Optimization of Plant Cell Culture Techniques for the Production of Bioactive Compounds from in-vitro Callus Culture of Citrus Maxima Peel" (Co-guide).
- Supported PhD study: "Bacterial DNA Fingerprinting from Selected Human Population" under the fellowship award of MP Council of Science and Technology, Bhopal for Dr. Toshi Jain. (2017-2021).
- Supported PhD Study: An international student from Cameroon under Research Training Fellowship for Developing Country Scientists (RTF-DCS) (July 2019-Dec 2019).
- Supported PhD study: A student from University of Hyderabad under an MoU for drug testing against resistant Mycobacterium tuberculosis and toxicity studies of the same. (2022-2023).
- Supported PhD study: A student from NCCS, Pune under collaboration with Dr. Shekhar Mande for physiological characterization of M.tb and deciphering the role of thioredoxin proteins in Mycobacterium tuberculosis probed by proteome-wide target profiling (2022-2023).
Ongoing research projects
- Antimicrobial Potential of Drugs Being Used in Alternative System of Medicine in India
- Exploration and validation of new drug targets for tackling antimicrobial resistance in Mycobacterium tuberculosis
- CpsA of Mycobacterium tuberculosis: Exploration of its potential as a novel drug target
Current research collaborators
Past research collaborators
- National Chemical Laboratory, Pune
- The Bioinformatics Centre (D.I.C) at the Savitribai Phule Pune University, Pune
- Hyderabad Central University, Hyderabad
- National Institute of Naturopathy, Pune
- Sant Hirdaram Medical College of Naturopathy & Yogic Sciences for Women, Bhopal
- NCCS, Pune
- Kumamoto University, Japan
- University of Nebraska Medical Center
- Bafoussam Regional Hospital, Cameroon
- Symbiosis International University, Pune
- Dr. D. Y. Patil Medical College and Research Centre, Pune
- BJ Medical College, Pune
Research in news
- Diesse, J.M., Jadhav, S., Tamekou, S.L. et al. Disturbances in the gut microbiota potentially associated with metabolic syndrome among patients living with HIV-1 and on antiretroviral therapy at Bafoussam Regional Hospital, Cameroon. Diabetol Metab Syndr 17, 86 (2025). DOI Link
Award/Recognition/Honours
- Awarded OAR-Sponsored scholarship to attend the 9th IAS Conference on HIV Science (IAS 2017), on 23-26 July 2017 at the Palais des Congrès in Paris, France.
- Selected for a three months Training Program in Biomedical Informatics at Vanderbilt University, USA under a training grant from the Fogarty International Centre of NIH. (Worked with Dr. Jens Meiler from 19 May to 17 Aug 2012).
- Patent awarded: Kamboj, D.V, Nema, V., Singh L., Krishanamurthy S., Goel, A. K. Process for the purification of single polypeptide chain protein. Application No: 2575/DEL/2007; Patent no. 284404. Application filed on: 07/12/2007; Date of grant: 21/06/2017.
- Honorary Rosalind Member of London Journals Press. Membership ID, #XI29968
Workshop/Conference Organized
N/A
Academic contributions
- Delivered lecture on advanced techniques in Molecular Biology for AcSIR PhD coursework on 21 Jan 2025
- Delivered an invited lecture/hands-on training to the Ph.D. scholars (Batch 2023) for the Second contact programme of Pre-Ph.D. coursework, FoMHS, Symbiosis International (Deemed University), Pune on 13 Jan 2024
- Delivered an invited guest lecture in international webinar on “21st Century: Research Innovations in Life Sciences in Relation to Human Welfare” organized by Dept. of Botany and Zoology, Govt. Autonomous Girls P.G. College of Excellence, Sagar, M.P. on the topic “Microbiome: an organ to be studied by modern science and to be correlated with old ones” on 21st July 2020
- Delivered an invited guest lecture under DBT-STAR college scheme at Prof. RamKrishna More College, Pune on the topic “Updates in HIV research” on 16th March 2019
- Delivered an invited guest lecture in National Seminar on, "Biodiversity of Environmental allergens and its impact on human health," on Microbiome connection of allergic diseases, held at Taywade College, Mahadula-Koradi, Nagpur on 9th Feb 2019
- Delivered an invited lecture entitled “Microbial Forensics: An emerging science” in Regional Seminar on Microbiome In Health And Disease sponsored by Indian Academy of Biomedical Sciences at Symbiosis University, Pune on 28 Sept 2018
- Delivered an invited guest lecture at Dr. D.Y.Patil Medical College, Pimpri, Pune on “Microbiome: A world within a body” on 20th April 2018
- Delivered a session as guest speaker at NIN under an awareness program on HIV and Naturopathy. Spoke on "Relevance of Naturopathy in HIV" on 04/12/2017
- Institutional Ethics Committee, National Institute of Naturopathy, Pune (Serving 2nd term)
- Member of Board of Studies at Abeda Inamdar Senior College Pune (2020-21)
- Member of Doctoral Research Committee (DRC) for Shivaji University, Kolhapur (2020-21)
Research Grants
Received funding from: ICMR Extramural Grant DHR extramural grant AYUSH (NIN Pune)
Publications
- Jogi, M. K., Shikha, S., Singh, P., Shreyansh, Paul, A., Nema, V., … Kumar, P. (2025). Short-read next-generation sequencing of 16s rRNA gene amplicons for characterizing amplicon sequence variants (ASVs) and determination of gene copy numbers using Ion Torrent platform. Nucleosides, Nucleotides & Nucleic Acids, 1–14. DOI (IF: 1.1)
- Diesse, J.M., Jadhav, S., Tamekou, S.L., et al. (2025). Disturbances in the gut microbiota potentially associated with metabolic syndrome among patients living with HIV-1 and on antiretroviral therapy at Bafoussam Regional Hospital, Cameroon. Diabetology & Metabolic Syndrome, 17, 86. DOI (IF: 3.4)
- Gaikwad, S.Y., More, A., Seniya, C., Verma, K., Chandane-Tak, M., Nema, V., et al. (2025). Synergistic inhibition of HIV-1 by Nelfinavir and Epigallocatechin Gallate: A novel nanoemulsion-based therapeutic approach. Virology, 603, 110391. DOI (IF: 2.8)
- Chatla, C., Mishra, N., Malathi, J., Nema, V., et al. (2024). Evaluation of urinary LAM assay versus conventional sputum microscopy for TB detection in HIV and non-HIV patients. Clinical Epidemiology and Global Health, 30, 101827. DOI (IF: 2.3)
- Jadhav, S., Nair, A., Mahajan, P., Nema, V. (2024). The Crosstalk Between HIV-TB Co-Infection and Associated Resistance in the Indian Population. Venereology, 3(4), 183–198. DOI
- Gupta, A., Pal, S.K., Nema, V. (2024). High frequency of silent mutations in gyrA gene of M. tuberculosis in Indian isolates. Environmental and Molecular Mutagenesis, 65(8), 289–293. DOI (IF: 2.3)
- Joshi, R., Aithal, S., More, A., Nema, V., Mukherjee, A. (2024). Therapeutic potential of silver nanocomposition of Catharanthus roseus for antimicrobial/antiviral use. Int. J. Plant-Based Pharmaceuticals, 4(2), 101–109. DOI
- Vadankula, G.R., Nilkanth, V.V., Rizvi, A., … Nema, V., et al. (2024). Quinoline-isonicotinic acid hydrazide hybrid compound as anti-TB agent. ACS Infectious Diseases, 10(6), 2288–2302. DOI (IF: 5.3)
- Nema, V., Jadhav, S. (2024). Significance of Upcoming Technologies in Microbial Diversity Research. In Microbial Diversity in the Genomic Era, 2nd Ed., ISBN: 9780443133206.
- Kumar, S., Taumar, D., Gaikwad, S., … Nema, V. (2023 Dec 31). Atazanavir-rosemary oil nanoformulation for HIV-1. Drug Delivery and Translational Research. DOI (IF: 5.4)
- Dhotre, K., Banerjee, A., Dass, D., Nema, V., Mukherjee, A. (2023). In-silico design of siRNA against Monkeypox. Current Pharmaceutical Design. DOI (IF: 3.1)
- Kamble, S., Nema, V., et al. (2023). TB infection control in HIV settings in India (2022). Int. J. Tuberc Lung Dis. Supp., 27(11). (IF: 4)
- Kamble, S., Bhandari, P., Nigam, S., Nema, V., et al. (2023). TB transmission control in HIV settings (2021–22). Int. J. Tuberc Lung Dis. Supp., 27(11). (IF: 4)
- Dhotre, K., Dass, D., Banerjee, A., Nema, V., et al. (2024). Designing siRNA for SARS-CoV-2 variants. Current Computer-Aided Drug Design, 20(6), 876–887. DOI (IF: 1.7)
- Sahoo, R., Jadhav, S., Nema, V. (2023). Technological advances in AMR detection. J Formos Med Assoc. DOI (IF: 3.2)
- Mahajan, P.S., et al., Nema, V. (2023). Drug resistance in M. tuberculosis and role of cell envelope proteins. Indian J Tuberc, 70(3), 286–296. DOI (IF: 2.6)
- Sugandhi, S., Jadhav, S., Nema, V., et al. (2023). Role of thioredoxin proteins in M. tuberculosis. Biochem Biophys Rep, 35, 101512. DOI (IF: 2.7)
- Jadhav, S., Nema, V. (2023). Viral/host genetics and neurocognitive disorders in HIV. AIDS Res Hum Retroviruses, Dec, 688–698. DOI (IF: 1.5)
- Shinde, M.D., Patil, S.A., Mukherjee, A., Nema, V. (2023). Homeopathic Rhus Tox for herpes and inflammation. J Ayurveda Integr Med, 14(4), 100739. DOI (IF: 2.4)
- Khan, A.A., Nema, V., Ashraf, M.T. (2023). Microbiota-oncogenesis crosstalk. Microb Pathog, 178, 106063. DOI (IF: 3.84)
- Jadhav, S., Makar, P., Nema, V. (2022). Neuroinflammatory potential of HIV-1 Nef variants. Cells, 11(20), 3256. DOI (IF: 6)
- Jadaun, P., Seniya, C., Kumar, P., Nema, V., et al. (2022). Anti-HIV potential of C-Phycocyanin. Antioxidants, 11(10), 1942. DOI (IF: 7)
- Mane, A., Jain, S., Nema, V., et al. (2022). Diagnostic accuracy of self-collected oral swabs for COVID-19. APMIS, 130, 671–677. DOI (IF: 2.8)
- Jadhav, S., Nema, V. (2021). HIV-associated neurotoxicity and protein interplay. Mediators Inflamm., 2021, Article ID 1267041. DOI (IF: 4.4)
- Waghmode, R., Jadhav, S., Nema, V. (2021). Burden of respiratory viruses in India (1970–2020). Front Microbiol, 12:723850. DOI (IF: 4)